Inhibition of Chikungunya virus genome replication by targeting essential RNA structures within the virus genome

doi:10.1016/j.antiviral.2023.105523

Article

Inhibition of Chikungunya virus genome replication by targeting essential RNA structures within the virus genome

2 Jan 2023

Abstract excerpt

Chikungunya virus (CHIKV) is a pathogenic arbovirus spread by Aedes spp. mosquitos. CHIKV has a wide global prevalence and represents a significant health burden in affected populations. Symptoms of CHIKV infection include fever, rashes and debilitating joint and muscle pain, which can persist for several months to years in some patients. To date, there remains no vaccine or specific antiviral therapy against...

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