Article

A common tag nucleotide variant in <i>MMP7</i> promoter increases risk for hypertension via enhanced interactions with CREB transcription factor

2019-03-06

Abstract excerpt

MMP7 (Matrilysin), a potent extracellular matrix degrading enzyme with wide substrate specificity, is emerging as a new regulator of cardiovascular diseases including coronary artery disease and atherosclerosis. However, potential contributions of MMP7 genetic variations to hypertension remain unknown. In this study, we first probed for the association of a tag single nucleotide polymorphism (SNP) in the MMP7 ge...

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Literature Corpus work: 7cc29cf4-d4f9-5ebb-af58-7b7a594fabad
DOI: 10.1101/568774

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