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Article

Polymorphisms of the matrix metalloproteinase genes are associated with essential hypertension in a Caucasian population of Central Russia.

Scientific reports - 4 Mar 2021

Moskalenko Maria, Ponomarenko Irina, Reshetnikov Evgeny, Dvornyk Volodymyr, Churnosov Mikhail

Abstract excerpt

This study aimed to determine possible association of eight polymorphisms of seven MMP genes with essential hypertension (EH) in a Caucasian population of Central Russia. Eight SNPs of the MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, and MMP12 genes and their gene-gene (epistatic) interactions were analyzed for association with EH in a cohort of 939 patients and 466 controls using logistic regression and assuming...

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Identifiers

PMID: 33664351
DOI: 10.1038/s41598-021-84645-4
PMCID: PMC7933364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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