Article

Polycystic ovary syndrome susceptibility loci inform disease etiological heterogeneity

2021-03-08

Abstract excerpt

<h4>Purpose: </h4> Polycystic ovary syndrome (PCOS) is a complex disorder with heterogenous phenotypes and unclear etiology. A recent phenotypic clustering study identified metabolic and reproductive subtypes of PCOS. We attempted to deconstruct the PCOS heterogeneity from a genetic perspective. Methods We applied k-means clustering to categorize the genome-wide significant PCOS variants into clusters based on the...

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Literature Corpus work: 7cb319e8-abc8-56a4-9f44-23e437b664fa
DOI: 10.1101/2021.03.04.21252927

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