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Deconstructing a Syndrome: Genomic Insights Into PCOS Causal Mechanisms and Classification

13 Jan 2022

Abstract excerpt

Polycystic ovary syndrome (PCOS) is among the most common disorders in women of reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria. PCOS is characterized by a constellation of interrelated reproductive abnormalities, including disordered gonadotropin secretion, increased androgen production, chronic anovulation, and polycystic ovarian morphology. It is frequently associated with...

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PMID: 35026001
DOI: 10.1210/endrev/bnac001

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