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Article

Polycystic Ovary Syndrome Physiologic Pathways Implicated Through Clustering of Genetic Loci.

The Journal of clinical endocrinology and metabolism - 15 Mar 2024

Stamou Maria I, Smith Kirk T, Kim Hyunkyung, Balasubramanian Ravikumar, Gray Kathryn J, Udler Miriam S

Abstract excerpt

CONTEXT: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, with disease loci identified from genome-wide association studies (GWAS) having largely unknown relationships to disease pathogenesis. OBJECTIVE: This work aimed to group PCOS GWAS loci into genetic clusters associated with disease pathophysiology. METHODS: Cluster analysis was performed for 60 PCOS-associated genetic variants and 49 traits...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to ATXN2 gene

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Source

Open in PubMed Open full text

Identifiers

PMID: 37967238
DOI: 10.1210/clinem/dgad664
PMCID: PMC10940264

Genes

ATXN2
CAD
FSHB
FTO
MAF
SH2B3
SLC38A11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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