Article

Mouse HP1γ regulates TRF1 expression and telomere stability

2022-11-24

Abstract excerpt

<h4>Aims</h4> TElomeric Repeat-containing RNA are long non-coding RNAs generated from the telomeres. TERRAs are essential for the establishment of heterochromatin marks at telomeres, which serve for the binding of Heterochromatin Protein 1 (HP1), a protein family of epigenetic modifiers involved with chromatin compaction and gene silencing. While HP1γ is enriched on gene bodies of actively transcribed human and m...

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Literature Corpus work: 7cad3f31-dbeb-571e-8971-d61895ed1512
DOI: 10.1101/2022.11.24.517673

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