Article
Peptide nucleic acid conjugates regulate gene expression in vitro : mode of action and new strategies for improved cellular uptake
2018-01-01
Abstract excerpt
RNA G-quadruplexes (G4) are an important class of nucleic acid secondary structures that are involved in mRNA translation, alternative splicing, localisation and 3'-end processing. Putative RNA G4 forming sequences have been identified in the regulatory regions of many disease-related genes, in particular oncogenes, and as a result have been of increasing interest as therapeutic targets for chemical intervention....
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Identifiers and source
- Literature Corpus work
- 7ca1b6d0-c13c-5bb7-9c95-cb47e419ec1c
- DOI
- 10.25560/65788