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Targeting RNA : A Transformative Therapeutic Strategy

1 Feb 2019

Abstract excerpt

The therapeutic pathways that modulate transcription mechanisms currently include gene knockdown and splicing modulation. However, additional mechanisms may come into play as more understanding of molecular biology and disease etiology emerge. Building on advances in chemistry and delivery technology, oligonucleotide therapeutics is emerging as an established, validated class of drugs that can modulate a...

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Identifiers

PMID: 30706991
DOI: 10.1111/cts.12624

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