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Genetic Analysis of Osteoblast Activity Identifies <i>Zbtb40</i> as a Regulator of Osteoblast Activity and Bone Mass

2019-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Osteoporosis is a genetic disease characterized by progressive reductions in bone mineral density (BMD) leading to an increased risk of fracture. Over the last decade, genome-wide association studies (GWASs) have identified over 1000 associations for BMD. However, as a phenotype BMD is challenging as bone is a multicellular tissue affected by both local and systemic physiology. Here, we focused...

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Literature Corpus work
d5ad5fe1-a7cf-5ca5-bda7-5bff41444895
DOI
10.1101/828525
Open publication

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Genetic Analysis of Osteoblast Activity Identifies <i>Zbtb40</i> as a Regulator of Osteoblast Activity and Bone MassDOI 10.1101/828525
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