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Rapid imaging of lysyl oxidase activity and fibrogenesis with a turn-on fluorophore

2026-05-18

Abstract excerpt

Fibrogenesis is essential to wound healing, but aberrant fibrogenesis is a driver of many chronic diseases and cancers. Lysyl oxidases (LOX) play a pivotal role in fibrogenesis by catalyzing the oxidation of lysine residues to reactive aldehydes (allysine) in collagens and elastin, resulting in the crosslinking and excessive deposition of these extracellular matrix components. Currently, rapid and robust histologi...

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Literature Corpus work
7c2efa9c-ef28-5d02-b8b8-fb0e305d3a86
DOI
10.64898/2026.05.14.725156
Open publication

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Rapid imaging of lysyl oxidase activity and fibrogenesis with a turn-on fluorophoreDOI 10.64898/2026.05.14.725156
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