Article

Landscape of Gene Mutation in Synovium of Patients with Rheumatoid Arthritis

2020-04-17

Abstract excerpt

<h4>Objective</h4> To investigate accumulating single nucleotide variants (SNVs) in synovium of patients with early, pre-treatment rheumatoid arthritis (RA). <h4>Methods</h4> I leveraged RNA-seq dataset derived from patients with RA deposited in database. To capture synovium-specific mutations, I applied standardized SNVs-calling method to paired synovium and blood samples per individual. <h4>Results</h4> De novo...

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Literature Corpus work: 7c26901c-4519-5378-b7d3-4c55d3f3c524
DOI: 10.1101/2020.04.14.20064592

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