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ALaSCA: A novel <i>in silico</i> simulation platform to untangle biological pathway mechanisms, with a case study in Type 1 Diabetes progression

2023-03-20

Abstract excerpt

<h4>Introduction</h4> The analysis of signaling pathways is a cornerstone in clarifying the biological mechanisms involved in complex genetic disorders. These pathways have intricate topologies, and the existing methods that are used for the interpretation of these pathways, remain limited. We have therefore developed the Adaptable Large-Scale Causal Analysis (ALaSCA) computational platform, which uses causal ana...

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Literature Corpus work
7c201f17-48b4-5e9e-b0d9-13a396877cf5
DOI
10.1101/2023.03.16.532913
Open publication

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