Article

Chandipura virus requires pro-survival RelA NF-κB function for its propagation

2019-01-02

Abstract excerpt

<h4>Summary</h4> In response to infection by RNA viruses, mammalian cells typically activate RelA-containing NF-κB heterodimers, which induce genes encoding interferon-β and other antiviral mediators. Therefore, RelA is commonly thought to function as an anti-viral transcription factor. Notably, virus-specific mechanisms often modify mainstay immune pathways. Despite its human health relevance, how Chandipura vir...

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Literature Corpus work: 7c1b43c5-14ab-5334-8779-e464b86a319b
DOI: 10.1101/509893

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