Article

Understand Variability of COVID-19 Through Population and Tissue Variations in Expression of SARS-CoV-2 Host Genes

2020-07-20

Abstract excerpt

An urgent question of coronavirus disease 2019 (COVID-19) is population variation in susceptibility to SARS-CoV-2 infection and symptom severity. We explore the expression profiles of SARS-CoV-2 host genes, their variations, age- and sex-dependency in the normal population. Genes exhibiting most variable expression include ACE2, CLEC4G, CLEC4M, CD209 (interact with the SARS-CoV-2 spike protein); REEP6 (a receptor...

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Literature Corpus work: 2544915f-e584-5ccd-82c8-2b10fe03b78e
DOI: 10.2139/ssrn.3653548

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