Article

Reduced glucose supply during neonatal infection attenuates neurological and renal pathology via modulation of innate and Th1 immunity

2024-05-17

Abstract excerpt

<h4>Background</h4> Premature infants are highly susceptible to infections that can lead to sepsis with life-threatening organ dysfunctions. The clinical practice of high parenteral glucose supply in preterm infants can exacerbate infection outcomes through excessive glycolysis-induced inflammatory response. This in turn can affect the health of vital preterm organs, including the brain and kidneys. We hypothesiz...

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Literature Corpus work: 7bdff1e7-0c91-5eba-ab83-5881a948f051
DOI: 10.1101/2024.05.15.594288

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