Article

Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoids

2023-12-12

Abstract excerpt

Endochondral ossification is a developmental process in the skeletal system and bone marrow of vertebrates. During endochondral ossification, primitive cartilaginous anlages derived from mesenchymal stem cells (MSCs) undergo vascular invasion and ossification. In vitro regeneration of endochondral ossification is beneficial for research on the skeletal system and bone marrow development as well as their clinical...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7bd30fe0-4ec0-51f0-ae47-9444aabdb3a0
DOI: 10.1101/2023.12.11.571194

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoidsDOI 10.1101/2023.12.11.571194Read

Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoids.Semantic proximity Read

Enhancing Cartilage Repair: Surgical Approaches, Orthobiologics, and the Promise of ExosomesSemantic proximity Read

Generation of a Bone Organ by Human Adipose-Derived Stromal Cells Through Endochondral Ossification.Semantic proximity Read

Kartogenin-mediated transformation of osteo-chondroprogenitors from stem cells facilitates bone repair via intramembranous and endochondral ossificationSemantic proximity Read

Notch1 signaling regulates Sox9 and VEGFA expression and governs BMP2-induced endochondral ossification of mesenchymal stem cellsSemantic proximity Read

Regenerative medicine and developmental biology: The role of the extracellular matrixSemantic proximity Read

Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation.Semantic proximity Read

Craniofacial chondrogenesis in organoids from human stem cell-derived neural crest cellsSemantic proximity Read

Silencing Smad7 Potentiates BMP2-induced Chondrogenic Differentiation and Inhibits Endochondral Ossification in Human Synovial Derived Mesenchymal Stem CellsSemantic proximity Read

An Organoid for Woven BoneSemantic proximity Read

Developmental Biology-Inspired Strategies To Engineer 3D Bioprinted Bone ConstructSemantic proximity Read

Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossificationSemantic proximity Read