Article
Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoids.
Biochemical and biophysical research communications - 15 Mar 2024
Notoh Hinako, Yamasaki Satoshi, Suzuki Nobuaki, Suzuki Atsuo, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Naruko, Katsumi Akira, Kojima Tetsuhito, Matsushita Tadashi, Tamura Shogo
Abstract excerpt
Endochondral ossification is a developmental process in the skeletal system and bone marrow of vertebrates. During endochondral ossification, primitive cartilaginous anlages derived from mesenchymal stem cells (MSCs) undergo vascular invasion and ossification. In vitro regeneration of endochondral ossification is beneficial for research on the skeletal system and bone marrow development as well as their clinical...
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