Article

The phage protein paratox is a multifunctional metabolic regulator of <i>Streptococcus</i>

2024-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Streptococcus pyogenes , or Group A Streptococcus (GAS), is a commensal bacteria and human pathogen. Central to GAS pathogenesis is the presence of prophage encoded virulence genes. The conserved phage gene for the protein paratox (Prx) is genetically linked to virulence genes, but the reason for this linkage is unknown. Prx inhibits GAS quorum sensing and natural competence by binding the trans...

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Literature Corpus work: 7bc01b05-f951-5a9d-a27e-6ea546d6098d
DOI: 10.1101/2024.08.02.605684

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