Article

SB939 is analyzed by STAT3 to inhibit breast cancer cell metastasis-related genes

2022-07-11

Abstract excerpt

<h4>Background: </h4> The histone deacetylase inhibitor (HDACi) Pracinostat (SB939) plays a vital role in inhibiting metastasis of triple-negative breast cancer by downregulating FN1 expression levels through the STAT3 signaling pathway.SB939 has low cytotoxicity and may become a new generation of targeted agents against breast cancer tumors. This study aimed to investigate the association value of STAT3 and FN1 a...

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Literature Corpus work: 7b8a4c12-edd6-54a6-b67f-0fc9c80c8a60
DOI: 10.21203/rs.3.rs-1804555/v1

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