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Potential therapeutic targets of the JAK2/STAT3 signaling pathway in triple-negative breast cancer

18 Apr 2024

Abstract excerpt

Triple-negative breast cancer (TNBC) poses a significant clinical challenge due to its propensity for metastasis and poor prognosis. TNBC evades the body's immune system recognition and attack through various mechanisms, including the Janus Kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway. This pathway, characterized by heightened activity in numerous solid tumors,...

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PMID: 38699644
DOI: 10.3389/fonc.2024.1381251

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