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Association between white-matter lesion volume and heart-rate variability: A comparison of T1, T1-T2 and T1-FLAIR-based segmentations using FreeSurfer SAMSEG

2025-11-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Heart disease is a crucial risk factor for brain degeneration, but the exact mechanisms are still under investigation. Notably, a growth in white-matter lesion (WML) volume, a hallmark of cerebral small-vessel disease (cSVD) with connections to progressive neurodegeneration and cognitive decline, has been linked to cardiovascular disease. As such, measures of cardiovascular...

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Literature Corpus work
7b8158f8-8a34-51cc-8bf5-307e94cfbcc4
DOI
10.1101/2025.11.18.689161
Open publication

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Association between white-matter lesion volume and heart-rate variability: A comparison of T1, T1-T2 and T1-FLAIR-based segmentations using FreeSurfer SAMSEGDOI 10.1101/2025.11.18.689161
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