Article

Conjecture: Some auto-immune diseases are caused by the tissue, not a problem with the immune system

2015-11-20

Abstract excerpt

Applying highly sensitive modern immune profiling techniques to the blood or inflamed tissue of auto-immune patients with one of the common T-cell mediated diseases fails to detect large clonal expansions or other signs of a dysregulated immune system. Additionally, these new methods have shown that self-reactive T-cells are found in the periphery (and are not completely negatively selected in the thymus as previo...

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Literature Corpus work: 7b6ed677-5b64-571f-8594-70ce3a3bb0f1
DOI: 10.1101/032300

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