[Pathogenic mechanisms of autoimmune diseases].

Abstract excerpt

BACKGROUND: Auto-immune diseases are a fascinating but poorly understood group of diseases. MAJOR POINTS: In this review, we will consider genetic susceptibility to auto-immune diseases, initiation of autoreactivity and changes in pathologic processes. Recent physiopathological hypotheses are detailed with clinical examples. PERSPECTIVES: A better knowledge of the physiopathological mechanisms would allow the...

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