Back to search

Article

TERT Promoter Mutations Contribute to Adverse Clinical Outcomes and Poor Prognosis in Radioiodine Refractory Differentiated Thyroid Cancer

2024-04-11

Abstract excerpt

<title>Abstract</title> <p>Telomerase reverse transcriptase promoter (TERTp) mutations are associated with non-radioiodine avidity. However, the role of these mutations in the clinical outcomes of patients with radioiodine-refractory differentiated thyroid cancer (RAIR-DTC) remains unknown. Herein, we aimed to analyze gene mutations and clinical manifestations to verify TERTp’s role in driving disease progression...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7b6986b8-dc8b-5c12-adc9-377b1ff78281
DOI
10.21203/rs.3.rs-4143830/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
TERT Promoter Mutations Contribute to Adverse Clinical Outcomes and Poor Prognosis in Radioiodine Refractory Differentiated Thyroid CancerDOI 10.21203/rs.3.rs-4143830/v1
TERT promoter mutations contribute to adverse clinical outcomes and poor prognosis in radioiodine refractory differentiated thyroid cancer.Semantic proximity
TERT Promoter Mutation Predicts Radioiodine-Refractory Character in Distant Metastatic Differentiated Thyroid Cancer.Semantic proximity
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas.Semantic proximity
Association between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis.Semantic proximity
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.Semantic proximity
Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM staging system in differentiated thyroid cancer patients.Semantic proximity
TERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer.Semantic proximity
The Correlation Between the Presence of BRAFV600E and TERT Promoter Mutation and the Response to Treatment with Iodine 131 in Differentiated Thyroid Cancer Patients.Semantic proximity
Clinical utility of TERT promoter mutations and ALK rearrangement in thyroid cancer patients with a high prevalence of the BRAF V600E mutation.Semantic proximity
Effect of BRAFV600E and TERT Promoter Mutations on Thyroglobulin Response in Patients With Distant-Metastatic Differentiated Thyroid Cancer.Semantic proximity
BRAF and TERT promoter mutations: clinical application in thyroid cancer.Semantic proximity
The role of TERT promoter mutations in postoperative and preoperative diagnosis and prognosis in thyroid cancer.Semantic proximity
Select a neighboring publication to make it the new centre.