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Genome-Wide Association Analysis Identifies Genetic Correlates of Immune Infiltrates in Solid Tumors

2017-02-04

Abstract excerpt

Therapeutic options for the treatment of an increasing variety of cancers have been expanded by the introduction of a new class of drugs, commonly referred to as checkpoint blocking agents, that target the host immune system to positively modulate anti-tumor immune response. Although efficacy of these agents has been linked to a pre-existing level of tumor immune infiltrate, it remains unclear why some patients ex...

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Literature Corpus work
7b49c3c9-511c-5fd3-91fb-cfd613a9b020
DOI
10.1101/106039
Open publication

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Genome-Wide Association Analysis Identifies Genetic Correlates of Immune Infiltrates in Solid TumorsDOI 10.1101/106039
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