Back to search

Article

Integrating a host transcriptomic biomarker with a large language model for diagnosis of lower respiratory tract infection

2024-08-29

Abstract excerpt

<h4>BACKGROUND</h4> Lower respiratory tract infections (LRTIs) are a leading cause of mortality worldwide and can be difficult to diagnose in critically ill patients, as non-infectious causes of respiratory failure can present with similar clinical features. <h4>METHODS</h4> We developed a LRTI diagnostic method combining the pulmonary transcriptomic biomarker FABP4 with electronic medical record (EMR) text assess...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7ad12648-6bed-54b9-b905-67eb26a4b302
DOI
10.1101/2024.08.28.24312732
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrating a host transcriptomic biomarker with a large language model for diagnosis of lower respiratory tract infectionDOI 10.1101/2024.08.28.24312732
Integrated Host/Microbe Metagenomics Enables Accurate Lower Respiratory Tract Infection Diagnosis in Critically Ill ChildrenSemantic proximity
Integrating Host Response and Unbiased Microbe Detection for Lower Respiratory Tract Infection Diagnosis in Critically Ill AdultsSemantic proximity
Integrating Host Response and Unbiased Microbe Detection for Lower Respiratory Tract Infection Diagnosis in Critically Ill AdultsSemantic proximity
GPT-4o and the Quest for Machine Learning Interpretability in ICU Mortality PredictionSemantic proximity
GeneLLM: A large language model-based framework reveals age-dependent transcriptomic heterogeneity in sepsis diagnosisSemantic proximity
A Four-Gene Signature from Blood to Exclude Bacterial Etiology of Lower Respiratory Tract Infection in AdultsSemantic proximity
Clinical Impact, Diagnostic Performance, and Prognostic Implications of Plasma Metagenomic Next-Generation Sequencing in Solid Organ Transplant RecipientsSemantic proximity
Developing an Early Diagnostic Signature and Deciphering the Microbial-Host Dynamics in Lower Respiratory Tract Infection (LRTI) in Paediatric Intensive Care Unit (PICU) PatientsSemantic proximity
irAE-GPT: Leveraging large language models to identify immune-related adverse events in electronic health records and clinical trial datasetsSemantic proximity
Large-Language-Model Mortality Risk Stratification in the Intensive Care Unit: A Benchmark Against APACHE IISemantic proximity
Multimodal artificial intelligence using entire electronic health record and complete pathogen genome data for patient outcome prediction from life-threatening infection: the SuperbugAI PlatformSemantic proximity
Novel Insights into the Application of Large Language Models in the Diagnosis and Treatment of Complex Cardiovascular Diseases: A Comparative StudySemantic proximity
Select a neighboring publication to make it the new centre.