Article

Developing an Early Diagnostic Signature and Deciphering the Microbial-Host Dynamics in Lower Respiratory Tract Infection (LRTI) in Paediatric Intensive Care Unit (PICU) Patients

2025-11-06

Abstract excerpt

<h4>Background: </h4> Lower respiratory tract infection (LRTI) is a leading cause of morbidity and mortality among children admitted to paediatric intensive care units (PICUs). Accurate diagnosis is complicated by the breadth the broad spectrum of pathogens involved and the overlap of symptoms with non-infectious respiratory problems, often leading to diagnostic delays. This study aimed to identify early diagnosti...

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Literature Corpus work: 4d300db2-4ede-5a8a-85e7-302e717aae10
DOI: 10.1101/2025.10.31.25335414

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