Chromosome-scale genome assembly of B10.RIII, an autoimmune susceptible mouse strain

Abstract excerpt

A vast majority of potential drug candidates are initially tested in mice before human trials, resulting in life-saving treatments and preventive measures. Hundreds of autoimmune disorders, including arthritis, lupus etc., affect millions of people all over the world. Studying those disorders using mouse models is crucial for understanding the disease mechanisms. Knowing the genome sequence of these mouse models w...

Topics

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• Genome
• High-Throughput Nucleotide Sequencing
• Mice, Inbred Strains
• Molecular Sequence Data
• Polymorphism, Single Nucleotide
• Sequence Alignment
• Sequence Analysis, DNA
• Spleen

Identifiers and source

Literature Corpus work

7ac8604d-7085-5683-9ec6-0d32fd03d10a

DOI

10.1101/2025.05.16.654505