Article

Tolerability and effect of inhibiting microfibrillar-associated protein 4 in small intestinal anastomotic healing

2025-09-11

Abstract excerpt

<title>Abstract</title> <p>Background Crohn’s disease often leads to strictures due to excessive extracellular matrix deposition and smooth muscle cell hyperplasia. Current stricture treatments include surgical and endoscopic interventions, but high recurrence rates remain a challenge. Microfibrillar-associated protein 4 (MFAP4) contributes to fibrosis in various tissues. The anti-MFAP4 antibody was evaluated for...

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Literature Corpus work: 7ac0d7e3-61ea-5e5a-a469-6f8a261150af
DOI: 10.21203/rs.3.rs-7132995/v1

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