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Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD

2021-09-25

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) continue to wreak havoc across the globe. Higher transmissibility and immunologic resistance of VOCs bring unprecedented challenges to epidemic extinguishment. Here we describe a monoclonal antibody, 2G1, that neutralizes all current VOCs and has surprising tolerance to mutations adjacent to or within its interaction epitope. C...

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Identifiers and source

Literature Corpus work
7a9b920b-d1dc-54af-9644-9fb4c8cde040
DOI
10.1101/2021.09.24.461616
Open publication

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Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBDDOI 10.1101/2021.09.24.461616
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