Article

A single ancestral <i>ANP32</i> locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase

2024-09-17

Abstract excerpt

Viral polymerases rely on cellular cofactors to support efficient transcription of viral genes and replication of the viral genome. The RNA-dependent RNA polymerase of influenza virus, an orthomyxovirus, requires cellular ANP32A or ANP32B proteins for genome replication. However, little is known about whether ANP32 proteins are required by other orthomyxoviruses like the tick-borne thogotoviruses. Recent structura...

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Literature Corpus work: 7a668801-39d1-5b86-a7db-d7cf1f89a8a8
DOI: 10.1101/2024.09.16.613268

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A single ancestral <i>ANP32</i> locus in ticks creates multiple protein variants that all support the Thogoto virus polymeraseDOI 10.1101/2024.09.16.613268Read

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