Article

Whole-Cell Proteomics Identifies Novel Regulators of Ciliogenesis Beyond the Axoneme

2025-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Motile cilia generate directional fluid flow critical for development and tissue homeostasis, and their dysfunction underlies a range of human diseases. Prior proteomic studies have focused on isolated axonemes, leaving the regulatory components of ciliogenesis located in other cellular compartments of multiciliated cells (MCCs) largely unidentified. To bridge this gap, we performed whole-cell p...

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Literature Corpus work: 7a47c8dc-2ad3-5c6b-ace2-efe9ce30411f
DOI: 10.1101/2025.05.20.655211

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