Article

Evolutionary proteomics uncovers ciliary signaling components

2017-06-22

Abstract excerpt

<h4>ABSTRACT</h4> Cilia are organelles specialized for movement and signaling. To infer when during animal evolution signaling pathways became associated with cilia, we characterized the proteomes of cilia from three organisms: sea urchins, sea anemones and choanoflagellates. From these ciliomes, we identified 437 high confidence ciliary candidate proteins conserved in mammals, including known regulators of Hh, G...

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Literature Corpus work: 63fee345-bc02-5c1d-a07f-8b4d88efd978
DOI: 10.1101/153437

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