Article

ColTapp, an automated image analysis application for efficient microbial colony growth dynamics quantification

2020-05-30

Abstract excerpt

Phenotypic heterogeneity occurs in a population of genetically identical bacteria due to stochastic molecular fluctuations and environmental variations. In extreme cases of phenotypic heterogeneity, a fraction of the bacterial population enters dormancy, and these metabolically inactive or non-dividing bacteria persist through most antibiotic challenges. These subpopulations of persister cells are difficult to stu...

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Literature Corpus work: 7a46844f-a76d-5460-a749-fadbea9a319e
DOI: 10.1101/2020.05.27.119040

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