Article

An epithelial-to-mesenchymal transition model recovers and predicts critical mutations underlying hepatic cancer stem cells emergence

2023-06-02

Abstract excerpt

<h4>Background: </h4> Cancer stem cells (CSCs) have the ability to form tumors, induce metastasis and resistance to chemotherapy. These cells are generated by the epithelium-mesenchymal transition, and its presence has been linked to a poor prognosis. In the case of hepatocellular carcinoma (HCC), it has been seen that the increase in stemness markers portends the death of the patient. Thus, it is essential to und...

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Literature Corpus work: 7a1cc5dc-ec6d-5551-b4ea-9ecebf846bf7
DOI: 10.21203/rs.3.rs-2877522/v1

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