Article

Inferring spatial gene expression from tissue images using large-scale histology foundation model with SpaFoundation

2025-08-11

Abstract excerpt

Spatial transcriptomics (ST) has revolutionized biological research by enabling the joint profiling of gene expression and spatial context, along with histological images. However, current existing ST technologies remain high-cost and time-consuming, hindering their broader clinical applications. Although computational methods have been developed to infer gene expression directly from histology images, these metho...

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Literature Corpus work: 6a05c033-eb7d-5968-ad75-e0cc777df9de
DOI: 10.1101/2025.08.07.669202

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