Article

β-endorphin primes Natural Killer cells and NK-derived Extracellular Vesicle to enhance anti-tumor cytotoxicity

2026-07-31

Abstract excerpt

Psychoneuroimmunology suggests that positive physiological states, including laughter, could affect anti-tumor immunity, but the underlying mechanisms remain unclear. Here, we investigated whether β-endorphin (BE), an endogenous opioid peptide associated with positive physiological stimuli, modulates Natural Killer (NK) cell cytotoxicity and the anti-tumor activity of NK-derived extracellular vesicles (EVs). Using...

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Literature Corpus work: 79ec9dca-64bb-5933-801b-56a844f75b4d
DOI: 10.64898/2026.07.29.741417

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