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Effect of luseogliflozin on bone microarchitecture in elderly patients with type 2 diabetes: Study protocol for a randomized controlled pilot trial using second-generation high-resolution peripheral quantitative computed tomography (HR-pQCT)

2020-03-23

Abstract excerpt

<title>Abstract</title> <p>Background Elderly patients with type 2 diabetes mellitus (T2DM) have an increased risk of bone fracture independent of their bone mineral density (BMD), which is explained mainly by the deteriorated bone quality in T2DM compared to non-diabetic adults. Sodium-glucose co-transporter (SGLT) 2 inhibitors have been studied in several trials in T2DM, and the Canagliflozin Cardiovascular Ass...

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Literature Corpus work
79cc110b-f9da-56ad-96b8-53c229b5f94b
DOI
10.21203/rs.2.14017/v2
Open publication

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