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Article

Fasting glucose, bone area and bone mineral density: a Mendelian randomisation study.

Diabetologia - 1 Jun 2021

Mitchell Adam, Larsson Susanna C, Fall Tove, Melhus Håkan, Michaëlsson Karl, Byberg Liisa

Abstract excerpt

AIMS/HYPOTHESIS: Observational studies indicate that type 2 diabetes mellitus and fasting glucose levels are associated with a greater risk for hip fracture, smaller bone area and higher bone mineral density (BMD). However, these findings may be biased by residual confounding and reverse causation. Mendelian randomisation (MR) utilises genetic variants as instruments for exposures in an attempt to address these...

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Identifiers

PMID: 33650017
DOI: 10.1007/s00125-021-05410-w
PMCID: PMC8099809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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