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Sec23a Inhibits The Self-Renewal of Melanoma Cancer Stem Cells via Inactivation of ER-Phagy

2021-06-22

Abstract excerpt

<title>Abstract</title> <p>Background The genesis and developments of solid tumors, analogous to the renewal of healthy tissues, are driven by a subpopulation of dedicated stem cells, known as cancer stem cells (CSCs), that exhibit long-tern clonal repopulation and self-renewal capacity. CSCs may regulate tumor initiation, growth, dormancy, metastasis, recurrence and chemoresistance. While autophagy has been pro...

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Literature Corpus work
7984f801-e012-54e0-9152-db1d242a6459
DOI
10.21203/rs.3.rs-579892/v1
Open publication

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Sec23a Inhibits The Self-Renewal of Melanoma Cancer Stem Cells via Inactivation of ER-PhagyDOI 10.21203/rs.3.rs-579892/v1
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