Article
Analysis of the transcriptome and DNA methylome in response to acute and recurrent low glucose in human primary astrocytes
2020-07-07
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Aims/hypothesis</h4> Recurrent hypoglycaemia (RH) is a major side-effect of intensive insulin therapy for people with diabetes. Changes in hypoglycaemia sensing by the brain contribute to the development of impaired counterregulatory responses to and awareness of hypoglycaemia. Little is known about the intrinsic changes in human astrocytes in response to acute and recurrent low glucose (RL...
Topics
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- Adipose Tissue and Metabolism
- Climate Change and Health Impacts
- Diabetes and associated disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- MicroRNA in disease regulation
- Pancreatic function and diabetes
- RNA Research and Splicing
- Thermoregulation and physiological responses
Identifiers and source
- Literature Corpus work
- 794c36f5-8455-5528-babb-5b719ce449ab
- DOI
- 10.1101/2020.07.07.191262
