Article

Extension of individual model averaging assessments to unbalanced designs and dose-response

2024-04-17

Abstract excerpt

1 Recent investigations assessed two non-linear mixed effect (NLME) model based approaches to test for drug effect on real data in the context of balanced two-arms designs. The standard approach (STD) showed type I error inflation and biased drug effect estimates contrary to the proposed alternative, individual model averaging (IMA), which had controlled type I error and unbiased drug effect estimates. The current...

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Literature Corpus work: 794c1aba-275a-5839-828e-c5af6fb1797c
DOI: 10.1101/2024.04.13.589390

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