Article

Mural cell SRF controls pericyte migration, vessel patterning and blood flow

2021-11-27

Abstract excerpt

<h4>Rationale</h4> Pericytes (PCs) and vascular smooth muscle cells (vSMCs), collectively known as mural cells (MCs), are recruited through PDGFB-PDGFRB signaling. MCs are essential for vascular integrity, and their loss has been associated with numerous diseases. Most of this knowledge is based on studies in which MCs are insufficiently recruited or fully absent upon inducible ablation. In contrast, little is kn...

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Literature Corpus work: 79480670-5ce9-51db-afad-b5f454f8d22f
DOI: 10.1101/2021.11.26.470022

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