Article

YAP activity is necessary and sufficient for basal progenitor abundance and proliferation in the developing neocortex

2018-09-23

Abstract excerpt

<h4>Summary</h4> The expansion of the neocortex during mammalian evolution has been linked to an enlargement of the subventricular zone during cortical development and an increase in the proliferation of the basal progenitors residing therein. Here, we explored a potential role of YAP, the major downstream effector of the Hippo signaling pathway, in proliferation of basal progenitors. We show that YAP expression...

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Literature Corpus work: 791dda74-0c56-5f04-937d-bdb45b41e828
DOI: 10.1101/416537

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