Article

Metformin Effects on Follistatin and Oxyntomodulin Levels and Its Relationship With Polycystic Ovaries Syndrome and Associated Comorbidities: Secondary Analysis of Randomized Double-blind Clinical Study.

2023-01-23

Abstract excerpt

<h4>Background: </h4> An abnormal secretion of incretins, specially Glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and oxyntomodulin (OXM), have been described in subjects with Type 2 diabetes mellitus and PCOS. OXM has important actions in the metabolism including the ability to reduce food intake and improve insulin secretion reducing the liver fat accumulation. Metformin is...

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Literature Corpus work: 78fde78d-6d88-5f49-a84a-851c3f013fc2
DOI: 10.21203/rs.3.rs-2375448/v1

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