Article

Effects of Metformin on Reproductive, Endocrine, and Metabolic Characteristics of Female Offspring in a Rat Model of Letrozole-induced Polycystic Ovarian Syndrome With Insulin Resistant

2020-12-09

Abstract excerpt

<h4>Background: </h4> Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disorder that has many characteristic features including hyperandrogenemia, insulin resistance and obesity. The beneficial effects of metformin on reproduction, metabolism and endocrine, especially with the capacity to ameliorate insulin resistance (IR) in polycystic ovary syndrome (PCOS), place it as a good alternative...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9b4ff382-236f-54ea-8afd-330cf27718b7
DOI: 10.21203/rs.3.rs-122468/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Effects of Metformin on Reproductive, Endocrine, and Metabolic Characteristics of Female Offspring in a Rat Model of Letrozole-induced Polycystic Ovarian Syndrome With Insulin ResistantDOI 10.21203/rs.3.rs-122468/v1Read

Metformin in Reproductive BiologySemantic proximity Read

Insulin resistance/hyperinsulinemia and reproductive disorders in infertile womenSemantic proximity Read

Metformin Effects on Follistatin and Oxyntomodulin Levels and Its Relationship With Polycystic Ovaries Syndrome and Associated Comorbidities: Secondary Analysis of Randomized Double-blind Clinical Study.Semantic proximity Read

Rodent models in polycystic ovarian syndrome: Dissecting reproductive and metabolic phenotypes for therapeutic advancements.Semantic proximity Read

Effects of Exogenous Adiponectin Supplementation in Early Pregnant PCOS Mice on the Metabolic Syndrome of Adult Female OffspringSemantic proximity Read

Signaling pathways and targeted therapeutic strategies for polycystic ovary syndromeSemantic proximity Read

Elevated Insulin-Like Growth Factor-1-Induced Female Rats Perpetuate the Polycystic Ovary Syndrome Phenotype: Pathological Mechanism of Insulin-Like Growth Factor-1 in Polycystic Ovary Syndrome.Semantic proximity Read

Research on the self-healing ability of polycystic ovarian syndrome (PCOS) in mice model and its impact on offspringSemantic proximity Read

Metabolic Syndrome and Infertility in WomenSemantic proximity Read

Orosomucoid 2 improves reproductive phenotypes in a mouse model of PCOS induced by letrozole under high-fat diet conditions.Semantic proximity Read

Differential Expression of microRNAs in the Ovaries from Letrozole-Induced Rat Model of Polycystic Ovary SyndromeSemantic proximity Read

Update on Animal Models of Polycystic Ovary SyndromeSemantic proximity Read