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Is Metformin a Perfect Drug? Updates in Pharmacokinetics and Pharmacodynamics.

Current pharmaceutical design - 1 Jan 2017

Markowicz-Piasecka Magdalena, Huttunen Kristiina M, Mateusiak Lukasz, Mikiciuk-Olasik Elzbieta, Sikora Joanna

Abstract excerpt

Metformin, a synthetic biguanide, is currently one of the most frequently recommended medications for type 2 diabetes treatment around the world. This review presents the latest discoveries in the pharmacokinetics of metformin, especially the role of transporters (e.g. Organic Cation Transporters OCTs, Multidrug and Toxin Extrusion transporters MATE) in oral absorption, distribution, elimination and biochemical...

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PMID: 27908266
DOI: 10.2174/1381612822666161201152941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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