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Mechanosensitive Piezo Channels Contribute to Airway Changes in Chronic Obstructive Pulmonary Disease

2026-06-17

Abstract excerpt

As an intrinsically mechanosensitive organ, the lung experiences a range of mechanical forces. Chronic obstructive pulmonary disease (COPD) involves abnormal macroscopic cellular and extracellular matrix (ECM) changes that impact mechanical properties of the lung. Mechanosensitive Piezo1/2 channels are expressed in the lung including on airway smooth muscle cells (ASM) that mediate cellular responses to stretch an...

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Literature Corpus work
787f27dc-c46e-5568-aa51-8f353f5ab14f
DOI
10.64898/2026.06.14.732150
Open publication

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Mechanosensitive Piezo Channels Contribute to Airway Changes in Chronic Obstructive Pulmonary DiseaseDOI 10.64898/2026.06.14.732150
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