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Article

Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Feb 2013

Gujar Shashi, Dielschneider Rebecca, Clements Derek, Helson Erin, Shmulevitz Maya, Marcato Paola, Pan Da, Pan Lu-Zhe, Ahn Dae-Gyun, Alawadhi Abdulaziz, Lee Patrick W K

Abstract excerpt

Immunosuppression associated with ovarian cancer (OC) and resultant peritoneal carcinomatosis (PC) hampers the efficacy of many promising treatment options, including immunotherapies. It is hypothesized that oncolytic virus-based therapies can simultaneously kill OC and mitigate immunosuppression. Currently, reovirus-based anticancer therapy is undergoing phase I/II clinical trials for the treatment of OC. Hence,...

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Identifiers

PMID: 23299799
DOI: 10.1038/mt.2012.228
PMCID: PMC3594021

Genes

FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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